Resistance mutation supply modulates the benefit of CRISPR immunity against virulent phages in Pseudomonas aeruginosa

CRISPR immunity is not universally beneficial and varies by phage identity
CRISPR immunity significantly reduced the efficacy of both single and paired phage treatments (Fig 1A, S1 Table: CRISPR strain, F1,16,842 = 57.03, p < 0.00001); efficacy descr… [18781 chars]